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A Girl Ate Leftover Potato Salad For Lunch. This Is What Happened To Her Liver.

A Girl Ate Leftover Potato Salad For Lunch. This Is What Happened To Her Liver.


A Girl Ate Leftover Potato Salad for Lunch. This is What Happened To Her Liver. CG is a 17 year old girl, presenting to the
emergency room with a progressive deterioration in balance, gait and speech. She tells the admitting nurse that she felt
a burning in her stomach over the past couple days. She had several stomach movements from one
particular end. You see, CG was an American high school student. On the weekends, she got to stay with her
dad in the city. Over the last couple of months, she started
noticing that she had trouble with balance, writing and speaking. Sometimes she had something to say, but she’d
have trouble getting the words out. One weekend, CG was with her dad. The only food he had in his fridge was homemade
potato salad. He was really proud of this one because he
made all the ingredients from scratch, including a new dill pickle recipe he found on the internet. Before his daughter heated up some leftovers,
he warned her that it was too delicious and that she wouldn’t be able to eat just one
serving. But he also told her that he felt some discomfort
from both ends after eating some a few days earlier. Ignoring both of these warnings, CG heated
up a large bowl of leftover potato salad. She was feeling great after eating it. She went back for seconds. And thirds. As the day continued, CG became incredibly
thirsty. She quickly gulped down 2 whole bottles of
water. Must have had a lot of salt in that potato
salad, she thought as she started doing her homework. Over the next few hours, CG felt a burning
sensation brewing in her stomach. It would come in waves. She didn’t want to complain to her dad about
it, because she didn’t want to hurt his feelings about his cooking. She kept quiet about everything. She saw a rash growing on the dorsum, or backside
of her hands, and decided to go to bed early. The next morning, CG woke up. There was no more rash on her hands, but her
entire body was in a world of hurt. The burning in her stomach was now accompanied
by a sharp prodding feeling in her side. Her joints all felt stiff. When she told her dad about this, he said
“welcome to old age,” as he left to go run some errands. As the day passed, CG found it increasingly
difficult to move. She started noticing that her skin was turning
a greenish yellow. She hiccuped. And then huddled over the sink. Something green came up. This kept happening, every hour. As the week continued, CG had to miss school
because she felt so ill. She couldn’t keep anything down. Every time she had to hiccup, it was followed
by another movement up and out. As she finally couldn’t take it anymore,
her mom called 911 and she’s brought to the emergency room where we are now. At examination, doctors noted that CG’s
stomach was distended, or swollen. She was clearly jaundiced as evidenced by
the yellowing of her skin and the whites of her eyes. Both of these are indicators that whatever’s
wrong with her, is coming from her liver. This gives the medical team some clues as
to what’s happening. CG noted a metallic taste had come up every
time she hiccuped, and as she was telling this to the medical team, she hiccuped again. And things came up again. And doctors saw it first hand. This could be some kind of food poisoning
from the potato salad she ate, except a blood test revealed anemia. An meaning without and emia meaning presence
of blood. There was something wrong with her red blood cells. That’s not something that usually comes
from food poisoning. Lab abnormalities from that blood test confirmed
liver dysfunction (students, can you give 3 examples of what these could be?), bringing
us to the next clue. The liver is important for several things
in the body. For starters, It makes proteins. Some of these proteins are blood clotting
factors, which stop you from bleeding when you get a cut. Other proteins known as albumin hold water
in specific compartments in the body, so that fluid isn’t flowing freely all throughout. And because of how it’s connected to the
small intestines, the liver processes all the nutrients that you put in your body, from
your mouth. This sets the stage for defining CG’s liver
problems because Her blood clotting factors aren’t working fast enough (students, how is INR defined?) meaning the liver might
be having trouble making them. And it might be having this trouble because something is preventing it from making those proteins But this measure was still in normal range, even if it was at the upper limit of normal. This could be a problem, maybe not. CG’s abdomen is swollen with fluid, something
called ascites and it means that that albumin isn’t being sufficiently produced by her
liver now. When combined with jaundice and anemia, all of this points to some degree of potential liver injury for CG. But what could be causing this? This brings us back to anemia. CG reported metallic taste in her mouth, and
a green emesis that followed her hiccups. This could be a problem of B vitamins. Both of these are generally greenish yellow
liquids. They’re stored in the liver. And, their deficiencies can cause anemia (students-
macro or microcytic anemia?), but CG didn’t have vitamin B deficiency. She was tested for iron and copper. These are actual metals– that could be contributing to her metallic taste Iron Deficiency causes anemia. This is because red blood cells hold on to
oxygen using hemoglobin, a protein that contains iron. And for copper, too little and too much, both
cause anemia. And in CG’s case, she has too much copper The medical team finds that she has hypercupremia. Hyper meaning high Cupro from latin Cuprum, which was borrowed
from Greek Κύπρος which is Cyprus in English. The island where western ancients got their
metals from. And emia meaning presence in blood. High copper presence in blood. But where did this copper come from, she ate
potatoes and why is it causing these problems? At this realization, CG’s dad tells the
medical team that he had gotten sick from the potato salad, in a similar fashion, just
not as severe. He recalled that he used a copper pot and
utensils that he bought from an antique store to prepare the pickles he put in that potato
salad. But how does copper from a pot and tongs,
get into pickles? Well, there’s some basic chemistry to be
known here. Copper when exposed to oxygen and moisture
in the air, reacts. This can happen to pots if they’re not coated
well. If it’s antique, there’s a good chance,
then there’s a good chance it wasn’t coated well (or at all). The moisture from condensation in the pot,
likely reacted with the copper and created something called copper oxide. This is exactly how old pennies got dirty,
because they’re made of copper too. When pickling vegetables, vinegar is used. Vinegar is an acid. Vinegar, reacts with copper oxide, picking
it off the pot, and putting it in the pickles,
and then into the potato salad. In the body, copper disrupts normal functions. Because CG ate it in the potato salad, it
traveled from her stomach, to her liver. And just like how it reacted with oxygen when
it was in the pot, it reacts with oxygen in her liver, creating reactive oxidative species,
that destroy everything. For CG, her mitochondria cannot be the powerhouse
of the cell because this reactive oxygen, disturbs energy production. Disrupting this metabolism, damages the cell. Additional injury is delivered to the DNA,
as CG’s liver cells all start to burst. And as this process happens at a cellular
level, the liver tissue becomes injured, causing problems with her blood clotting factors causing problems with albumin production causing impaired uptake of bilirubin, causing jaundice everything that is happening to CG. If too much copper is her problem, is there
a way we could somehow remove that copper from her body? Maybe. Because copper likes to react with oxygen,
and it does so by pulling electrons away, then we can ask a heavier element, similar
to oxygen, to react with copper instead? On the outside of this molecule, we want it
to dissolve in water, so that it can be removed by the kidneys, and put in the urine. CG was given Penicillamine. Not the antibiotic penicillin. Penicillamine. The sulfur and nitrogen capture the copper,
and the entire complex is filtered by her kidneys, and released in her urine. After 8 days in the hospital, CG was discharged,
as she seemed to make a recovery. More visits with her dad prompted her to never
again, eat any of his cooking, even if he vowed to never use antiques to cook. But as the weeks go by, CG doesn’t seem
to be ok. After discharge from the hospital, that deterioration
in balance, gait and speech she had before eating the potato salad, was getting worse. Even though she never again ate her dad’s
food, her mom started noticing her jaundice again. At school, rumors started going around that
CG was going to have a baby. Her stomach had a bump. She’d be found before class in the bathroom,
huddled over the toilet, with what looked like morning sickness. And during class, she had to leave the room,
because she couldn’t stop sweating. Back in the emergency room again, CG tells
the doctors about a burning in her stomach. She is found to have ataxic gait. A meaning without and taxic meaning order. Gait being her walk. It was awkward, imbalanced, disorderly. This was combined with dystaxic handwriting
and slurred speech, all of which can point to some potential neurodegeneration, not found
when she ate that potato salad. meaning something has been happening since then Jaundice and ascites are found, again. A blood test this time reveals that her clotting
factors, are just not working properly now (students- INR limit for acute liver failure?). They were borderline last time, but it’s
clear now that something’s wrong. Usually, a liver problem on this scale like
this would cause mental status change (hepatic encephalopathy) This is because the liver processes ammonia
that comes from a breakdown of proteins in your GI tract. But if the liver is failing, this ammonia
spills into the body, and goes to the brain. But now the question is, does CG have liver
injury, or liver failure? It’s important to make the distinction because
failure is much more severe than the injury. Jaundice, ascites, and the blood test confirm
something’s wrong with her liver. The clotting factor problem is an emergency
because it can lead to something terrible, if nothing is done about it. In adults, it’s hard to qualify liver failure,
without the mental status change. But CG isn’t an adult. She’s 17. Her motor dysfunctions are not mental status
change. About half of pediatric patients can present
without this, and still have acute liver failure. And in CG, she has acute liver failure. Ultrasound finds that her gallbladder is swollen. Inside, there appears to be a sludge that
has been building up over time. Bile is a fluid made by the liver, and stored
in the gallbladder, that helps the body digest fats. This sludge means that CG’s liver could
be making something, that it shouldn’t be. A calculation is made on her blood test results. With 100% specificity and sensitivity, the
calculation reveals that CG has Wilson’s Disease, a genetic disease that prevents the
liver from eliminating copper from the body. (students, what is this Wilson’s disease
test?). She is immediately transferred to the intensive
care unit, and evaluated for liver transplantation, because what’s left of her current liver,
is beyond repair. This Wilson’s disease is something that
had been brewing for sometime in CG, and was made much worse when she ate that potato salad. In humans, copper has to be shuttled around
by proteins. We’ve already shown how reactive copper
is when alone and flowing freely in the body. But in Wilson’s disease, an inherited genetic
defect prevents the correct production of this protein, meaning its ability to transport
copper is impaired. Causing it to build up. Causing damage to the liver cells by creating
reactive oxidative species. This forms a sludge in the gallbladder as
the acute liver failure in CG causes permanent damage. As the copper spills into the bloodstream,
it enters the brain. In normal function, the same protein as found
in the liver also transports copper out. But because of the genetic defect, that doesn’t
happen. Copper accumulates in the brain, and this
metal toxicity begins to damage nerve cells, permanently. Showing up as motor dysfunction in CG. Copper in Wilson’s Disease often deposits in the eyes as a complex with sulfur, forming a brownish or gray-green ring. This happens often in Wilson’s disease, but not all the time. It can also happen when there’s problems of bile flow from the liver, in patients without Wilson’s Disease But in the intensive care unit, the medical team
calculates a score to predict her survival, given the results of her blood test. (King’s criteria btw). A score higher than 11 gives little chance
of survival without liver transplant. And in CG, it’s higher than 11. She is immediately placed, on the liver transplantation
list. Because she was noted to have acute liver
failure instead of injury, her placement is high. Because her life expectancy is less than 7
days because of the extent of her disease, she was placed at the very top of the list. Days pass while she’s in waiting. A donor was finally located. A 19 year old who sustained a head injury
and passed because of shock. CG undergoes transplantation and transferred
to the transplant unit afterwards. She received medicines that suppressed her
immune system, so that it wouldn’t attack her new liver. 10 days after the operation, she was sent
home, and monitored. Her new liver was from a donor who didn’t
have Wilson’s disease. Meaning, those liver cells do not have the
genetic defect that she inherited, and they can make the protein that transports copper,
curing her from the disease. But the DNA in her body, still has those genes. When she has kids, they will at a minimum
be a carrier for the defect, if they don’t have Wilson’s disease themselves. And if they’re carriers, there’s a chance
that CG’s grandkids will be affected in the same way, as she was when she had this
critical illness. But with the new liver, and support from her
family. With a father who learned to never pickle
foods using copper containers, or really, use anything copper at all for cooking, CG
made a good recovery. Thank you so much for watching. Take care of yourself and be well.

Comments (100)

  1. heme ?review ?
    PS: CC/Subtitles ON ✅ -> They have additional commentary for students ?‍⚕️?‍⚕️

  2. This is crazy, who heats up potato salad?!

  3. You are getting a bit too artsy with the photography, it’s not necessary and a bit distracting. It’s cool but maybe if you could do 2/3 of it/half but it would be better. Just my commentary, I love what you do you’re a charismatic guy and you should be doing very well for yourself.

  4. The father got really really sick from eating the potato salad but kept it in the fridge raider and said how great it was for his daughter. She knew about how sick he got an ate it anyway. This may be a story of natural selection.

  5. Another great video! Thank you!

  6. I gagged when he said the pickles were prepared in a copper pot.

  7. I'm never eating anything ever again.

  8. Living People

    AW: drinks lava lamp Living
    CC: eats cookie dough Living
    DA: eats potato chips, fries and white bread, becoming blind Presumably Living
    JR: eats laundry pods Living
    JC: suffers from Multi-organ failure Living
    BG: eats 25 laxative brownies Living
    JD: perforates her colon Living
    TJ: eats 150 gummy vitamins Living
    LE: ruptures blood vessel in her brain by eating a heap of chocolates Living
    DD: gets a parasite from his cat while Immunosuppressed Living
    JP: gets permanent brain damage from lead poisoning Living
    CJ: becomes massively dehydrated from excessive blood glucose levels after losing his son and mother, leaving his ex-wife and father Living
    MC: catches fever, suffering kidney failure Living
    CS: drinks homemade liquor Living
    MJ eats a heap of cookies Living
    JB drinks rum after dad introduces him to wine, then abandoning him 3 years later Living
    CG: drinks soy sauce and becomes brain dead Living
    GP: eats nachos and hot dogs, becoming temporarily disabled Living
    KT: grows beard Living
    JC: tries Keto diet, goes wrong, suffering insulinoma Living
    TB: eats sushi, and other spoiled food Living
    CG: suffers an inherited disease (Wilson’s Disease) after eating leftover potato salad Living

    Deceased People

    AJ: eats pasta contaminated with b. cereus Deceased
    JS (KC in the video): drinks water, suffers SIADH Deceased (Living in the video)
    DC: plays video games for 73 hours, has a lung attack and possibly a heart attack Deceased
    KC: removes his own skin cancer with pocket knife, suffering a brain hemorrhage Deceased
    KW: spills organic dimethylmercury on her hand Deceased

    This makes ABSOLUTELY NO sense!

    Likes:
    I
    I
    I
    I
    /

  9. The metal on the picture looks more like steel to me, chips from a mill or lathe.

  10. Man, these videos are great! You make them so well!!! I've learned so much and I can't get enough of them!!! I don't know if you'll ever see this but just in case, I wanted to tell you that I really appreciate the effort and the time you put in these videos! Thank you so, so much for making and sharing them!

  11. I don't know whether to like or dislike this video! Very informative, but overly dramatic!

  12. Sees parents cooking with cooper.

    Me: Imma head out…

  13. I love these. I learn so much! ❤️

  14. What Happen when you drink Cow Milk ,Its literally do more damage than other soda drinks

  15. A Boy Ate Shredded Cheese At 2 AM. This Is What Happened To His Parents Marriage.

  16. Me: Sips water
    Chubbyemu: A woman took a sip of water
    Me: Ah shit here we go again

  17. Yeah that's a crappy deal when someone cooks something for someone and they get sick – I mean, unless you were trying to poison them…

  18. Would someone kindly explain what happened? I'd rather not watch 15 minutes of fluff.

  19. Wow. Super great video. Super great.

  20. ☝️
    Presenting to the emergency room

  21. A cat ate his hoomam this is what happened to his catfood

  22. Damn that potato salad

  23. It's from heating the salad. Who TF heats up potato salad??? WTF

  24. I forgot why I subscribed to this channel in the first place and haven’t watched any videos in a while cause I thought they were like shitposts

  25. Heated up potato salad? You fuckin what. I'm not sure what kind of damn potato salad ya'll got but potato salad is a cold dish

  26. I miss home. Love seeing snapshots. Huh….who heats up mayo.

  27. I have a leftover casserole in my fridge… good luck to me

  28. Another great video, thank you for uploading! Can’t wait for the next one ☺️

  29. Just started the vid but I’m guessing she’s dying from the dad fermenting the pickles wrong

  30. CG is presenting to the emergency room experiencing weakness in the knees, his palms are sweaty, and theres vomit on his sweater already

  31. i cant imagine how guilty the father feels

  32. Is the medicine they used to suppress her immune system derived from the cordyceps fungus? Cause I’ve heard the spores help to suppress the immune system, which can be used for organ transplant patients

  33. Who heats up potato salad tho??

  34. 6:05 more like acidic chemistry

  35. Hears “homemade dill pickles” immediately sweats in canning nerd.

  36. What? Internet pickles! And the world is still turning on it's axis. Alert the media.

  37. CG is a 17 year old girl ☝ presenting..

  38. so she get ill because of cu(ac)2 in the salad or morbus wilson?
    Or did the cu in the salad speed up the disease?

  39. i remember wilson’s disease from the show House!!!

  40. OMG, I'm having an anxiety attack and so is poor liver. Daddy! Step away from the potato salad. And excuse me, every pickle recipe says don't use a Fucking copper pot.

  41. Boo! I hate happy endings.?

  42. The music Chubbyemu plays is boss music

  43. Why does her liver look like potatos

  44. …but why would you heat potato salad???

  45. For people in a developed country, I wonder how being diagnosed with a heritable disease like this would affect their decision to have children.

  46. Who warms up potato salad!????

  47. Who heats up potato salad?

  48. This is why we can’t eat anything at all

  49. Alhamdulillah, for my good health.

  50. 4:48 Says "PSA: Don't eat 150 of these at once"

  51. And now I'm scared of anything copper on store shelves

  52. Obviously a weak individual

  53. Wait, she heated, the potato salad. Heated it. That is so messed up. Poor CG.

  54. This channel makes me afraid of doing anything but I can’t stop watching

  55. This would be like the reincarnation of Dr. House if it had moar sarcasm.

  56. Recommended: "How to make world's best potato salad"

  57. 3:42 the dude pulled an ?

  58. In the old days, people used to put vinegar in lead cups then drink it for its sweetness …. it was called sugar of lead, which is also toxic. I'm wondering if it is as toxic as this though … this story is definitely a cautionary tale

  59. 4:48 PSA: DON'T EAST 150 OF THESE AT ONCE ??

  60. 7:00 The powerhouse of the cell

  61. “Every seed goes through the tremendous struggle of losing itself – losing its safety and integrity and becoming vulnerable to every outside force that’s around. But without that vulnerability, without the breaking, without the shedding of the shell, life won’t sprout.”
    ―     Jaggi Vasudev,   Pebbles Of Wisdom

  62. #1. You are awesome! Great narration; concise explanation of terminology (thank you so much for that); attractive presentation/presenter; personable, knowledgeable, genial; altogether the best video presentation I've seen in some time. #2. Pat yourself on the back and thank yourself (or your parents–whomever paid for your education) and know you will go quite far. This was a pleasure to watch and I loved the message: NO MORE COPPER POTS—EVER! JC could not have said it any better. ?

  63. “One should use information and logic as a drunkard would use a lamp post, only for support, not for illumination.”
    ―     Jaggi Vasudev,   Mind is your Business

  64. WHY DO I WATCH THESE IT JUST MAKES ME MORE SCARED IM GONNA DIE EVERY SECOND

    no offense to you im just venting

  65. Twists and turns in this intestinal teaser.

  66. Where was the mother while all this was going on?

  67. no one:
    absolutely nobody:
    chubbyemu: __ are__ this is what happened to their liver

  68. first of all, how are you gonna eat potato salad WARM

  69. 4:48 – flashed on screen
    That is true.

  70. who heats up potato salad?? wtf

  71. Like that throwback to the other video at 4:48 sec lol

  72. Everybody gangsta until the song goes

    Dun dun dun dun
    dun dun
    DUN DUN

  73. It's dangerous to heat mayonnaise too.

  74. And my parents wonder why I refuse to eat thanksgiving leftovers?

  75. Me: *stops video just to see chubbyemu say don’t eat 150 gummies in a day and the powerhouse the cell.

  76. A 20 year old woman, drinks water.
    this is what happened

  77. "CG" should have chopped up that mole on her face to make some guacamole instead.

  78. I hate the father.

  79. Ahhhhhhhhhh, I've missed your voice

  80. So her father ruined her life before she was even born and again after??

  81. I’d thank heaven, but she only made it because that other kid died. I wish I understood the world better sometimes. Like the man says, take care of yourself, and be well.

  82. I hate potato salad even more now.

  83. Who tf warms up potato salad

  84. Guide to never appear on one of Chubbyemu's videos:
    Step 1: Never eat/drink anything weird
    Step 2: Don't born with a strange disease
    Step 3: Have relatives that actually care about you

  85. These case studies are excellent. Like House MD but more realistic and provides more explanation than drama.

  86. Would CG actually have children after a liver transplant? Unless its a surrogate but then they could select a non-carrier embryo….

  87. jarvis used aimbot for a long time. this is what happend to his account.

  88. This show made me scared of any leftovers lmao. ?

  89. Time to worry if I might die tomorrow

  90. 8:00 discharged from hospital. Video length 14 mins. Me: SHE'S GONNA DIE!!

  91. why the hell you heat up potato salad…

  92. Ill never eat leftovers ever again

  93. A leftover potato salad girl ate liver. This is what happened to its lunch

  94. Kim Jong Un launches another missile.

    This is what happened to the lunchtime news on TV

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